SELECT 
  pfv.feature_id, 
  pfv.product_id, 
  pfv.variant_id, 
  fv.position, 
  fvd.variant 
FROM 
  cscart_product_features_values AS pfv 
  INNER JOIN cscart_product_feature_variants AS fv ON pfv.feature_id = fv.feature_id 
  AND pfv.variant_id = fv.variant_id 
  INNER JOIN cscart_product_feature_variant_descriptions AS fvd ON pfv.variant_id = fvd.variant_id 
  AND fvd.lang_code = 'en' 
WHERE 
  pfv.feature_id IN (22421, 19956, 22419, 22418, 19952) 
  AND pfv.product_id IN (26136, 5728, 286, 289, 5734) 
  AND pfv.lang_code = 'en'

Query time 0.01258

JSON explain

{
  "query_block": {
    "select_id": 1,
    "nested_loop": [
      {
        "table": {
          "table_name": "pfv",
          "access_type": "range",
          "possible_keys": [
            "PRIMARY",
            "fl",
            "variant_id",
            "lang_code",
            "product_id",
            "fpl",
            "idx_product_feature_variant_id"
          ],
          "key": "idx_product_feature_variant_id",
          "key_length": "12",
          "used_key_parts": ["product_id", "feature_id", "lang_code"],
          "rows": 25,
          "filtered": 0.110272586,
          "attached_condition": "pfv.feature_id in (22421,19956,22419,22418,19952) and pfv.product_id in (26136,5728,286,289,5734) and pfv.lang_code = 'en'",
          "using_index": true
        }
      },
      {
        "table": {
          "table_name": "fv",
          "access_type": "eq_ref",
          "possible_keys": ["PRIMARY", "feature_id"],
          "key": "PRIMARY",
          "key_length": "3",
          "used_key_parts": ["variant_id"],
          "ref": ["dev_db.pfv.variant_id"],
          "rows": 1,
          "filtered": 100,
          "attached_condition": "fv.feature_id = pfv.feature_id"
        }
      },
      {
        "table": {
          "table_name": "fvd",
          "access_type": "eq_ref",
          "possible_keys": ["PRIMARY"],
          "key": "PRIMARY",
          "key_length": "9",
          "used_key_parts": ["variant_id", "lang_code"],
          "ref": ["dev_db.pfv.variant_id", "const"],
          "rows": 1,
          "filtered": 100,
          "index_condition": "fvd.lang_code = 'en'"
        }
      }
    ]
  }
}

Result

feature_id product_id variant_id position variant
22419 286 78651 2 Cyan
22418 289 78649 0 Brown
19956 5728 69745 0 Green
19952 5734 69718 0 Beige
22421 26136 78656 0 Yellow